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RSO Dosage Plan: Complete Beginner to Advanced Protocol

Master Rick Simpson Oil dosing with our comprehensive 90-day protocol guide

22 min readUpdated Jan 2025Expert Protocol
RSO Rick Simpson Oil glass jar with cannabis leaf illustration, medical dosing syringe, and molecular chemistry symbols - Rick Simpson Oil dosage protocol guide

Rick Simpson Oil (RSO) dosing requires careful planning and gradual progression. This comprehensive guide provides a structured protocol from beginner to advanced levels, helping you safely navigate your RSO journey with confidence.

Quick Dosage Overview

Beginner

1/4 grain

3x daily

Week 1-2

Intermediate

1/2 grain

3x daily

Week 3-8

Advanced

1 gram

daily total

Week 9-12+

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Phase 1: Beginner Protocol (Weeks 1-2)

Starting Dose: 1/4 Grain of Rice

  • Size Reference: Approximately 25mg or the size of a short-grain rice piece cut into quarters
  • Frequency: 3 times daily (morning, afternoon, evening before bed)
  • Total Daily Dose: Approximately 75mg (25mg x 3)

Week 1-2 Schedule

TimeDoseNotes
Morning (8-9 AM)1/4 grain (25mg)Take with breakfast
Afternoon (2-3 PM)1/4 grain (25mg)Take with lunch or snack
Evening (9-10 PM)1/4 grain (25mg)Take 1 hour before bed

What to Expect in Week 1-2

  • - Mild relaxation and potential drowsiness (especially in evening doses)
  • - Slight appetite increase
  • - Improved sleep quality
  • - Mild digestive adjustments (normal - your body is adapting)
  • - Possible mild headache (stay hydrated!)
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Phase 2: Intermediate Protocol (Weeks 3-8)

Increased Dose: 1/2 Grain of Rice

  • Size Reference: Approximately 50mg or half of a short-grain rice piece
  • Frequency: 3 times daily (maintaining the same schedule)
  • Total Daily Dose: Approximately 150mg (50mg x 3)

Week 3-8 Progression

Weeks 3-4: Double the Dose

Increase from 1/4 grain to 1/2 grain at each dosing time. Monitor how your body responds.

Tip: If you experience increased drowsiness, reduce the afternoon dose slightly and keep evening dose higher for better sleep.

Weeks 5-6: Stabilization

Maintain 1/2 grain 3x daily. Your body should now be accustomed to this level.

Notice: You may feel normal and less drowsy as tolerance builds. This is expected and positive.

Weeks 7-8: Preparation for Full Dose

Continue 1/2 grain 3x daily while preparing to potentially increase to full therapeutic dose (1 grain).

Assessment: Evaluate your symptom relief and tolerance level before progressing.

What to Expect in Weeks 3-8

  • - Increased therapeutic effects for pain, inflammation, and symptom relief
  • - Better tolerance - less drowsiness than initial weeks
  • - Consistent sleep improvements
  • - Appetite normalization
  • - Potential mood stabilization and reduced anxiety

Ready to Start Your RSO Journey?

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Medical Disclaimer

This dosing guide is for educational purposes only and does not constitute medical advice. RSO is a potent cannabis extract and should be used responsibly. Consult with a healthcare professional familiar with cannabis therapeutics before beginning any RSO protocol, especially if you have pre-existing health conditions or take prescription medications. Start low, go slow, and adjust based on your individual response. Cannabis laws vary by location - ensure RSO is legal in your area before purchasing or using.